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Chemical basis for variation in the major antigenic site eliciting neutralizing antibodies in foot-and-mouth disease virus. Alexander, R. Gerin, D. Rolands, and F. Molecular basis of antivirus serotype specificity. Clevinger, S. McMillan, A. Srouji, R. Chemical synthesis of idiotypes: Evidence that antisera to the same JH1 peptide to detect multiple binding site-associated idiotypes. Alternative sources of hepatitis B vaccine. Standard , Wilson, I. Niman, R. Houghten, A. Cherenson, M. Connolly, and R. The structure of an antigenic determinant in a protein. Milner, J. Gottesfeld, and R.
Identifier sequences are transcribed specifically in brain. Dillner, J. Sternas, B. Kallin, H. Alexander, Ehlin-Henriksson, H. Antibodies against a synthetic peptide identify the Epstein-Barr virus determined nuclear antigen. Lamb, J. Zanders, P. Lake, R. Webster, D. Eckels, J. Woody, N. Lerner and M. Inhibition of T cell proliferation by antibodies to synthetic peptides. Purcell, and R.
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Proteins of the sea urchin egg vitelline layer. Developmental Biology , The structure of proteins in solution as revealed by antibodies to predetermined sites. Immunology Convocation, Tainer, J. Getzoff, H. Olson, R. The reactivity of anti-peptide antibodies is a function of the atomic mobility of sites in a protein. Gv-1 locus coordinately regulates the expression of multiple endogenous murine retroviruses. Cell, The immunology of synthetic peptides. In: Contemporary Topics in Molecular Immunology, Getzoff, Y. Paterson, A. Olson, and R.
The atomic mobility component of protein antigenicity. Getzoff, E. Tainer, and R. The chemistry of antigen-antibody union. Feldman, N. The influence of antigen conformation on the activation and induction of unresponsiveness in cloned human T lymphocytes, The use of synthetic peptides to identify protective epitopes of the hepatitis B surface antigen. Vaccines, Moriarty, A. Alexander, G. Thornton, and R. Antibodies to peptides detect new hepatitis B antigen: Serological correlation with hepatocellular carcinoma. Dietzschold, T. Wiktor, M. Kiel, R. Sutcliffe and H.
T-cell responses to cleaved rabies virus glycoprotein and to synthetic peptides. The structure and functional determinants of proteins as revealed by antibodies to predetermined sites. In: Trends in Pharmacological Sciences, Koprowski, M. The Gv-1 locus coordinately regulates the expression of multiple endogenous murine retroviruses. Haft, E. Getzoff, J. Tainer, R. Lerner, and S. Identical short peptide sequences in unrelated proteins can have different conformations: A testing ground for theories of immune recognition.
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Catalytic Antibodies. CSH Vaccines Vol. III, pp. Ricksten, A. Dillner, R. Fahraevs, G. Klein, R. Lerner, and L. Acad Sci. Satterthwait, A. Arrhenius, R. Hagopian F. Zavala, V. Nussenzweig, and R. The conformational restriction of peptidyl immunogens with covalent replacements for the hydrogen bond. Nobel Symposium, Vaccine Vol. Folding of peptide fragments of proteins in water solution 1.
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Sastry, W. Sorge, S. A combinatorial system for cloning and expressing the catalytic antibody repertoire in E. CSH Symp. Synthesis and Characterization of a recombinant myohemerythrin protein encoded by a synthetic gene. Gene , Weinhouse, D. Bait and switch strategy for obtaining catalytic antibodies with acyl-transfer capabilities. Huse, W. Sastry, S. Iverson, A. Kang, M. Alting-Mees, D. Burton, S. Generation of a large combinatorial library of the immunoglobulin repertoire in phage lambda.
Stanfield, R. Crystal structures of an antibody and its complex with peptide antigen at 2. Dyson, J. Satterthwait, R. Conformational Preferences of synthetic peptides derived from the immunodominate site of the circumsporozoite protein of plasmodium falciparum by 1H NMR. Biochemistry , Schultz, P.
Catalytic antibodies. Chemical and Engin. News, , Persson, M. Increased yield of antibody-producing murine spleen cell hybridomas from fusions cultured in medium supplemented with mouse serum. Immunological Methods, , Observations in the interface between immunology and chemistry. Chemtracts-Organic Chemistry, , Iverson, V. Roberts, E. Benkovic and R. Benkovic, R. Lerner, E. Getzoff and J. Antibody remodeling: A general solution to the design of a metal-coordination site in an antibody binding pocket.
Adams, C. Borders, Jr. The enzymic nature of antibody catalysis: Evolution of multistep kinetic processing. Ashley, T. Jones, D. McLeod, D. Schloeder, M.
Weinhouse, R. Gibbs, P. Hilhorst and S. Catalytic antibodies with acyl transfer capabilities: Mechanistic and kinetic investigations. Benkovic, D. Schloeder and R. Substrate Attenuation: An approach to improve antibody catalysis. However, because of its often quantitative basis and the amount of technical jargon, the subject tends to alienate and intimidate students.
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